How Does Skin Needling Work?As each fine needle punctures the skin, it creates a channel or micro-wound. The microchannels created spontaneously close after 10 mintues so that epidermal barrier integrity remains intact.
The needles injure superficial dermal collagen strands and small blood vessels triggering a controlled cascade of inflammation including the release of platelet-derived growth factors transforming growth factor-alpha and beta (TGF B-3) connective tissue activating protein, connective tissue growth factor, and fibroblast growth factor. These lead to the production of new collagen, elastin and capillaries.
